A 841720 is a potent, non-competitive mGluR-1 antagonist that displays 34-fold selectivity over mGluR-5 (IC|50|values are 10 and 342 nM respectively). A 841720 displays no significant activity at a range of other GPCRs, ion channels and transporters. This compound also exhibits analgesic effects, decreases mechanical allodynia in models of neuropathic pain, and impairs cognitive function.
a potent & non-competitive mGluR-1 antagonist
Specifications & Purity: A 841720 is a potent, non-competitive mGluR-1 antagonist that displays 34-fold selectivity over mGluR-5 (IC|50|values are 10 and 342 nM respectively). A 841720 displays no significant activity at a range of other GPCRs, ion channels and transporters. This compound also exhibits analgesic effects, decreases mechanical allodynia in models of neuropathic pain, and impairs cognitive function.
Grade: Moligand™
Molecular Formula: C17H21N5OS
Molecular Weight: 343.45
PubChem CID: 11559235
Isomeric SMILES: CN(C)C1=C2C3=C(C(=O)N(C=N3)N4CCCCCC4)SC2=NC=C1
Storage Temperature: Protected from light;Store at -20°C;Argon charged
Shipped in: Ice chest + Ice pads
More Information: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/A345272-SCI_c4b83858bd4d1714ac492110bdc065f7.pdf
- UPC:
- 41113631
- HazmatClass:
- Yes
- WeightUOM:
- LB
- MPN:
- A345272-1mg
- Country of Origin:
- China
- CAS:
- 869802-58-4
- Product Size:
- 1mg
- Harmonized Tariff Code:
- 2931.90.90
- Precautionary Statement Codes:
- P264
akash.verma@cenmed.com
(732) 447-1115





