A 841720 is a potent, non-competitive mGluR-1 antagonist that displays 34-fold selectivity over mGluR-5 (IC|50|values are 10 and 342 nM respectively). A 841720 displays no significant activity at a range of other GPCRs, ion channels and transporters. This compound also exhibits analgesic effects, decreases mechanical allodynia in models of neuropathic pain, and impairs cognitive function.
Specifications and Purity: ≥98%
Molecular Formula: C17H21N5OS
Molecular Weight: 343.45
PubChem CID: 11559235
Isomeric SMILES: CN(C)C1=C2C3=C(C(=O)N(C=N3)N4CCCCCC4)SC2=NC=C1
Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/A345272-SCI_c4b83858bd4d1714ac492110bdc065f7.pdf
- UPC:
- 41113631
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- A345272-10mg
- CAS:
- 869802-58-4
- Product Size:
- 10mg
- Precautionary Statement Codes:
- P264
akash.verma@cenmed.com
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