5-BROMO-2 4-DICHLOROPYRIMIDINE 97% (C005B-035781)

General description

5-Bromo-2,4-dichloropyrimidine is a halogenoprimidine. It has been reported as an intermediate during the synthesis of 2,4-di-t-butoxy-5-bromopyrimidine and 2,4-di-t-butoxy-5-pyrimidineboronic acid.

Application

5-Bromo-2,4-dichloropyrimidine may be employed as starting reagent for the synthesis of positive allosteric modulators for GABA_B receptors (drug-like class of compounds) and pyridinepyrimidine analogs.

Molecular Weight: 227.87. Empirical Formula: C₄HBrCl₂N₂. Quality Level: 100. Assay: 97%. form: solid. refractive index: n20/D 1.603 (lit.). bp: 128 . °C/15 . mmHg (lit.). mp: 29-30 . °C (lit.). density: 1.781 . g/mL . at 25 . °C (lit.). SMILES string: Clc1ncc(Br)c(Cl)n1. InChI: 1S/C4HBrCl2N2/c5-2-1-8-4(7)9-3(2)6/h1H. InChI key: SIKXIUWKPGWBBF-UHFFFAOYSA-N. Pictograms: GHS05,GHS06. Signal Word: Danger. Hazard Statements: H301 + H311 + H331 - H314 - H317. Precautionary Statements: P260 - P271 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338. Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1. Storage Class Code: 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials. WGK: WGK 3. Flash Point(F): 235.4 °F - closed cup. Flash Point(C): 113 °C - closed cup. Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges, type P3 (EN 143) respirator cartridges.