5-AMINO-4 6-DICHLOROPYRIMIDINE 97% (C005B-047698)

Application

5-Amino-4,6-dichloropyrimidine was used in the synthesis of:

• oxepane ring containing monocyclic, conformationally restricted bicyclic and spirocyclic nucleosides
• conformationally locked bicyclo[2.2.1]heptane/oxa-bicyclo[3.2.1]octane nucleosides
• N(7)-substituted purines
• chiral derivatives of (+)-erythro-9-(2-hydroxy-3-nonyl)adenine
• 9-alkyl-6-substituted-purine analogs, potent anticonvulsant agents
• pyrimido-oxazepines in a three-step process with microwave heating at 150°C

Molecular Weight: 163.99. Empirical Formula: C₄H₃Cl₂N₃. Quality Level: 100. Assay: 97%. form: liquid. mp: 145-148 . °C (lit.). solubility: 95% ethanol: soluble 50 . mg/mL, clear to slightly hazy, colorless to faintly yellow. storage temp.: 2-8°C. SMILES string: Nc1c(Cl)ncnc1Cl. InChI: 1S/C4H3Cl2N3/c5-3-2(7)4(6)9-1-8-3/h1H,7H2. InChI key: NIGDWBHWHVHOAD-UHFFFAOYSA-N. Pictograms: GHS07. Signal Word: Warning. Hazard Statements: H315 - H319 - H335. Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338. Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3. Target Organs: Respiratory system. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves.