3 4-DIFLUOROPHENYLMAGNESIUM BROMIDE 0.5M SOLUTION IN TETRAHYDROFURAN

Application

3,4-Difluorophenylmagnesium bromide can be used:

• To prepare 3,4-difluorophenylboronic acid, a key building block employed in the synthesis of norepinephrine transporter selective molecules.
• In the synthesis of trimethoxybenzophenone derived tubulin polymerization inhibitors.
• In one of the key synthetic steps for the preparation of diarylketoxime derivatives as potent MCH-1R antagonists.
• In the synthesis of biologically important hydroxybupropion analogs useful in smoking cessation.

Legal Information

Product of Rieke Metals, Inc.
Rieke is a registered trademark of Rieke Metals, Inc.

Molecular Weight: 217.29. Empirical Formula: C₆H₃BrF₂Mg. linearFormula: F₂C₆H₃MgBr. reaction suitability: reaction type: Grignard Reaction. Quality Level: 100. concentration: 0.5 . M in THF. bp: 65 . °C. density: 0.965 . g/mL . at 25 . °C. storage temp.: 2-8°C. SMILES string: Fc1ccc([Mg]Br)cc1F. InChI: 1S/C6H3F2.BrH.Mg/c7-5-3-1-2-4-6(5)8. . /h1,3-4H. 1H. /q. . +1/p-1. InChI key: WZHAVYGMKGPNFN-UHFFFAOYSA-M. Pictograms: GHS02,GHS07,GHS08. Signal Word: Danger. Hazard Statements: H225 - H302 - H319 - H335 - H351. Precautionary Statements: P210 - P280 - P301 + P312 + P330 - P305 + P351 + P338 - P370 + P378 - P403 + P235. Hazard Classifications: Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3. Target Organs: Respiratory system. Supp Hazards: EUH019. Storage Class Code: 3 - Flammable liquids. WGK: WGK 3. Flash Point(F): 1.0 °F - closed cup. Flash Point(C): -17.2 °C - closed cup.