2-BENZYLOXYPHENYLMAGNESIUM BROMIDE 1.0M SOLUTION IN TETRAHYDROFURAN

Application

2-Benzyloxyphenylmagnesium bromide can be used:

• As a substrate in the iron-catalyzed coupling reaction of aryl Grignard reagents with unprotected bromophenols.
• As a substrate in the cross-coupling of Grignard reagents using diaryl titanates and ferric chloride.
• In one of the key synthetic steps for the total synthesis of an antibiotic caboxamycin.

Molecular Weight: 287.43. Empirical Formula: C₁₃H₁₁BrMgO. reaction suitability: reaction type: Grignard Reaction. Quality Level: 100. concentration: 1.0 . M in THF. density: 1.047 . g/mL . at 25 . °C. SMILES string: Br[Mg]c1ccccc1OCc2ccccc2. InChI: 1S/C13H11O.BrH.Mg/c1-3-7-12(8-4-1)11-14-13-9-5-2-6-10-13. . /h1-9H,11H2. 1H. /q. . +1/p-1. InChI key: VELKJPFZDYXBDE-UHFFFAOYSA-M. Pictograms: GHS02,GHS05,GHS07,GHS08. Signal Word: Danger. Hazard Statements: H225 - H302 - H314 - H335 - H351. Precautionary Statements: P210 - P260 - P280 - P305 + P351 + P338 - P370 + P378 - P403 + P235. Hazard Classifications: Acute Tox. 4 Oral - Carc. 2 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3. Target Organs: Respiratory system. Supp Hazards: EUH014 - EUH019. Storage Class Code: 3 - Flammable liquids. WGK: WGK 3. Flash Point(F): -4.0 - 5.0 °F - closed cup. Flash Point(C): -20 - -15 °C - closed cup. Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter.