ZL0420 (C007B-318495)

Catalog No.: C007B-318495
Manufacturer No.: Z414164-100mg
Manufacturer Name: Aladdin Scientific
Quantity: 1
Unit of Measure: EA

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Description
Specifications

InformationZL0420 ZL0420 is a potent and selective BRD4 inhibitor with IC50 values of 27 nM against BRD4 BD1 and 32 nM against BRD4 BD2 respectively and good selectivity over that of the related BRD2 homolog.TargetsBRD4 BD1 (Cell-free assay); BRD4 BD2 (Cell-free assay) 27 nM; 32 nMIn vitroZL0420 has a relatively high clearance and low exposures with oral bioavailability not favorable in vivo. Intravenous administration of ZL0420 gives an excellent drug exposure (high AUC value) and moderate half-life.

Specifications and Purity: ≥98%

Molecular Formula: C16H16N4O2

Molecular Weight: 296.32

PubChem CID: 137285011

Isomeric SMILES: CC1=CC(=C(C=C1O)N)N=NC2=CC3=C(C=C2)NC(=O)CC3

UPC:: 41102701
Condition:: New
HazmatClass:: No
WeightUOM:: LB
MPN:: Z414164-100mg
CAS:: 2229039-45-4
Product Size:: 100mg

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