Product Application:Z-VAD-FMK has been used: to induce mixed-lineage kinase domain-like (MLKL) phosphorylation (p-MLKL) in L929 cells to induce autophagy in Jurkat and K562 cells to revert killing effects of oxaliplatin or oxaliplatin combination with chloroquine (CQ) on HCT116 and SW620 cell lines as a caspase inhibitor to inhibit apoptosis and assess nuclear factor-kB, heat shock protein 70 (Hsp 70), proto-oncogene (cmyc) and tumor suppressor protein p53.
Specifications and Purity: ≥98%
Molecular Formula: C22H30FN3O7
Molecular Weight: 467.49
PubChem CID: 5497174
Isomeric SMILES: C[C@@H](C(=O)N[C@@H](CC(=O)OC)C(=O)CF)NC(=O)[C@H](C(C)C)NC(=O)OCC1=CC=CC=C1
Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/V275259-SCI_3d1ea569cc2ba40c72506f95231a149d.pdf
- UPC:
- 51141514
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- V275259-100mg
- CAS:
- 187389-52-2
- Product Size:
- 100mg
- Precautionary Statement Codes:
- P264
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