YS-370 (compound 44) is a potent, high selective, and orally active inhibitor of P-glycoprotein ( P-gp ). YS-370 stimulates the P-gp ATPase activity and has moderate inhibition against CYP3A4. YS-370 effectively reverses multidrug resistance (MDR) to paclitaxel and colchicine in SW620/AD300 and HEK293T-ABCB1 cells. YS-370 in combination with paclitaxel achieves much stronger antitumor activity.Form:Solid.
Specifications and Purity: ≥98%
Molecular Formula: C37H35BrN4O3
Molecular Weight: 663.60
- UPC:
- 41115408
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- Y646618-25mg
- CAS:
- 2470908-79-1
- Product Size:
- 25mg
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