XANTHOTOXIN

General description

Xanthotoxin is an allelochemical or a phototoxic allomone mainly found in host plants of black swallowtail. It can have the tendency to induce tolerance towards Α-cypermethrin, a pyrethroid insecticide used for insects like Helicoverpa zea.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

8-methoxypsoralen (8-MOP) plus ultraviolet A (UVA) irradiation induces monoadducts and interstrand cross-links in DNA and therefore can be used to study DNA repair and recombination mechanisms. Cultured normal human melanocytes treated with 8-methoxypsoralen and irradiated with ultraviolet A (UVA) formed 8-methoxypsoralen-phospholipid photoadducts that could be substituted for diacylglycerol to activate protein kinase C in a cell-free system. 8-MOP is an inactivator of purified reconstituted cytochrome P450. It also inhibits substance P-induced histamine release from substance P-activated rat peritoneal mast cells by suppressing the rise in [Ca²⁺].

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Molecular Weight: 216.19. Empirical Formula: C₁₂H₈O₄. grade: analytical standard. Quality Level: 100. Assay: ≥. 98% (GC). shelf life: limited shelf life, expiry date on the label. technique(s): HPLC: suitable, gas chromatography (GC): suitable. mp: 148-150 . °C (lit.). application(s): cleaning products
cosmetics
food and beverages
personal care. format: neat. storage temp.: 2-8°C. SMILES string: COc1c2OC(: O)C: Cc2cc3ccoc13. InChI: 1S/C12H8O4/c1-14-12-10-8(4-5-15-10)6-7-2-3-9(13)16-11(7)12/h2-6H,1H3. InChI key: QXKHYNVANLEOEG-UHFFFAOYSA-N. Pictograms: GHS07,GHS08. Signal Word: Warning. Hazard Statements: H302 - H317 - H341 - H351. Precautionary Statements: P202 - P261 - P280 - P301 + P312 - P302 + P352 - P308 + P313. Hazard Classifications: Acute Tox. 4 Oral - Carc. 2 - Muta. 2 - Skin Sens. 1. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.