X-34 (C005B-311414)

Catalog No.: C005B-311414
Manufacturer No.: SML1954-5MG
Manufacturer Name: Sigma-Aldrich
Quantity: 5
Unit of Measure: MG

Biochem/physiol Actions Fluorescent, amyloid-specific dye X-34 (1,4-bis(3-carboxy-4-hydroxyphenylethenyl)-benzene) is one among the small-molecule γ:-secretase modulators (GSMs) involved in lowering Aβ:42 levels (the 42-residue isoform of

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Description
Specifications

Biochem/physiol Actions

Fluorescent, amyloid-specific dye

X-34 (1,4-bis(3-carboxy-4-hydroxyphenylethenyl)-benzene) is one among the small-molecule γ-secretase modulators (GSMs) involved in lowering Aβ42 levels (the 42-residue isoform of the amyloid-β peptide). X-34 has also been used to visualize intracellular immunoreactive deposits with classic amyloid fibrillar ultrastructure in living transgenic Caenorhabditis elegans animals. It is also used as a histochemical stain for determining pathological changes in Alzheimer′s disease (AD).

X-34 is a fluorescent, amyloid-specific dye. It binds at a different site than Pittsburgh Compound B and is a highly fluorescent marker for beta-sheet structures.

UPC:: 85121808
Condition:: New
HazmatClass:: No
MPN:: SML1954-5MG
CAS:: 215294-98-7

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