WYE-354 is a potent, specific and ATP-competitive inhibitor of mTOR with IC50 of 5 nM, blocks mTORC1/P-S6K(T389) and mTORC2/P-AKT(S473) not P-AKT(T308), selective for mTOR than PI3Kα (>100-fold) and PI3Kγ (>500-fold).A potent, specific, and ATP-competitive inhibitor to mTOR with IC50 of 5 nM.
Specifications and Purity: ≥98%
Molecular Formula: C24H29N7O5
Molecular Weight: 495.54
PubChem CID: 44219749
Isomeric SMILES: COC(=O)NC1=CC=C(C=C1)C2=NC3=C(C=NN3C4CCN(CC4)C(=O)OC)C(=N2)N5CCOCC5
Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/W128007-SCI_312f872c104918f10121fc1c6bc7d1ad.pdf
- UPC:
- 41114406
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- W128007-100mg
- CAS:
- 1062169-56-5
- Product Size:
- 100mg
akash.verma@cenmed.com
(732) 447-1115





