WM-8014 (C007B-308785)

Catalog No.: C007B-308785
Manufacturer No.: W413571-100mg
Manufacturer Name: Aladdin Scientific
Quantity: 1
Unit of Measure: EA

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Description
Specifications

InformationWM-8014 WM-8014 is a highly potent inhibitor of histone acetyltransferase KAT6A with an IC50 of 8 nM.TargetsKAT6A (Cell-free assay) 8 nMIn vitroWM-8014 induces cell cycle arrest in embryonic day (E)14.5 mouse embryonic fibroblasts.Cells treated with WM-8014 failed to proliferate after ten days of treatment (IC50 2.4 μM). Higher doses of WM-8014 (up to 40 μM) did not accelerate growth arrest, which after eight days of treatment was irreversible.In vivoWM-8014 potentiates oncogene-induced senescence in a zebrafish model of hepatocellular carcinoma.

Specifications and Purity: ≥99%

Molecular Formula: C20H17FN2O3S

Molecular Weight: 384.42

PubChem CID: 133053564

Isomeric SMILES: CC1=CC(=CC(=C1F)C(=O)NNS(=O)(=O)C2=CC=CC=C2)C3=CC=CC=C3

UPC:: 41114404
Condition:: New
HazmatClass:: No
WeightUOM:: LB
MPN:: W413571-100mg
CAS:: 2055397-18-5
Product Size:: 100mg

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