VINYLMAGNESIUM BROMIDE 1.0M SOLUTION IN TETRAHYDROFURAN (C005B-022804)

Application

Vinylmagnesium bromide solution (1 M in THF) may be used in the synthesis of 2-vinylchroman-4-ones by the conjugate addition with chromones in the presence of a Lewis acid.
It may also be used in the following transformations:

• (S)-3-(benzyloxy)-4-oxo-butanoic acid methyl ester to methyl (3S,4S)-4-hydroxy-3-(phenylmethoxy)hex-5-enoate.
• (R)-1-Azido-5,6-epoxyhexane to (S)-1-(4-azidobutyl)-2-propen-1-ol.
• 2,3-O-Isopropylidene-D-ribose to 1-[(4R,5S)-5-((1S)-1-hydroxyallyl)-2,2-dimethyl[1,3]dioxolan-4-yl]ethane-1,2-diol.
• (4S,5S)-2,2-Dimethyl-5-vinyl[1,3]dioxolane-4-carbaldehyde to (1R,4R,5S)- and (1S,4R,5S)-1-(2,2-dimethyl-5-vinyl[1,3]dioxolan-4-yl)prop-2-en-1-ol.
• Ethyl levulinate to ?-methyl-?-vinylbutyrolactone.

Packaging

View returnable container options.

Other Notes

Storage below 25°C may cause crystallization. Warm gently to redissolve.

Molecular Weight: 131.25. Empirical Formula: C₂H₃BrMg. linearFormula: CH₂: CHMgBr. Quality Level: 100. reaction suitability: reaction type: Grignard Reaction. concentration: 1.0 . M in THF. density: 0.981 . g/mL . at 25 . °C. SMILES string: Br[Mg]C: C. InChI: 1S/C2H3.BrH.Mg/c1-2. . /h1H,2H2. 1H. /q. . +1/p-1. InChI key: XHHHAXOHMKAOSL-UHFFFAOYSA-M. Pictograms: GHS02,GHS05,GHS07,GHS08. Signal Word: Danger. Hazard Statements: H225 - H260 - H302 - H314 - H335 - H336 - H351. Precautionary Statements: P210 - P231 + P232 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338. Hazard Classifications: Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1A - Water-react 1. Supp Hazards: EUH019. Storage Class Code: 4.3 - Hazardous materials, which set free flammable gases upon contact with water. WGK: WGK 1. Flash Point(F): 1.4 °F. Flash Point(C): -17.0 °C. Personal Protective Equipment: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter.