Biochem/physiol Actions Vatiquinone (EPI-743), a metabolite of a-tocotrienol, is an orally available and highly potent analog of coenzyme Q10 that modulates the activity of oxidoreductases including AD(P)H:quinone oxidoreductase 1, resulting in
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Vatiquinone (EPI-743), a metabolite of a-tocotrienol, is an orally available and highly potent analog of coenzyme Q10 that modulates the activity of oxidoreductases including AD(P)H:quinone oxidoreductase 1, resulting in increased cellular GSH concentration and improvement in redox status. Vatiquinone is an agent designated to treat mitochondrial diseases.
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