UK-14 304 (C005B-285149)

Catalog No.: C005B-285149
Manufacturer No.: U104-100MG
Manufacturer Name: Sigma-Aldrich
Quantity: 100
Unit of Measure: MG

Application UK 14,304 has been used for the activation of extracellular signal-regulated kinase (ERK) in epicardial coronary artery culture UK 14,304 has been used in myenteric neurons to study the inhibition of R-type calcium currents . UK

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Description
Specifications

Application

UK 14,304 has been used for the activation of extracellular signal-regulated kinase (ERK) in epicardial coronary artery culture

UK 14,304 has been used in myenteric neurons to study the inhibition of R-type calcium currents. UK 14,304 has also been used for immunofluorescence microscopy assays.

Biochem/physiol Actions

UK 14,304 is an α2-adrenoceptor agonist. UK 14,304 inhibits hormone-sensitive lipase (HSL) activity and suppresses lipogenesis in adipose tissue.

Features and Benefits

This compound is featured on the α2-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Preparation Note

UK 14,304 is soluble in 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin (<0.8 mg/mL), DMSO (>6.5 mg/ml) and ethanol (<8 mg/mL). However, it is insoluble in water.

UPC:: 41104506
Condition:: New
HazmatClass:: Yes
MPN:: U104-100MG
CAS:: 59803-98-4

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