TYLOSIN TARTRATE VETRANAL (C005B-227369)

General description

Tylosin tartrate is a tylosin derivative and a medium spectrum antibiotic, which can find applications in veterinary medicine for the treatment of infections caused by most gram-positive bacteria, mycoplasmas, some gram-negative bacteria and chlamydia bacteria. It can also be used as a feed additive in order to improve the weight gain and feed efficiency of cattle, poultry, turkey and swine.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Tylosin is a mcrolide antibiotic commonly used in veterinary medicine. It has been used to study protein synthesis at the 50S ribosome, implant site abscess prevention in cattle, disposition kinetics and Mycoplasma gallisepticum and Mycoplasma meleagridis infections. It is recommended for use in cell culture applications at 8 mg/L.

Biochem/physiol Actions

Mode of Action: Tylosin Tartrate inhibits bacterial protein synthesis by binding to the 50S (L27 protein) ribosome.

Antimicrobial Spectrum: This product acts against gram-positive bacteria and mycoplasma.

Components

This product is a mixture of tylosin A, B, C, and D tartrates.

Caution

Stock solutions should be filter sterilized and stored at 2-8°C. These solutions are stable at 37°C for 3 days.

Legal Information

VETRANAL is a registered trademark of Sigma-Aldrich Chemie GmbH

grade: analytical standard. Quality Level: 100. product line: VETRANAL^®. . shelf life: limited shelf life, expiry date on the label. technique(s): HPLC: suitable, gas chromatography (GC): suitable. application(s): pharmaceutical (small molecule). format: neat. storage temp.: 2-8°C. SMILES string: O[C@H]([C@@H](O)C(O): O)C(O): O.CC[C@H]1OC(: O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O[C@H]3C[C@@](C)(O)[C@@H](O)[C@H](C)O3)[C@@H]([C@H]2O)N(C)C)[C@@H](CC: O)C[C@@H](C)C(: O)\C: C\C(C): C\[C@@H]1CO[C@@H]4O[C@H](C)[C@@H](O)[C@@H](OC)[C@H]4OC. InChI: 1S/C46H77NO17.C4H6O6/c1-13-33-30(22-58-45-42(57-12)41(56-11)37(52)26(5)60-45)18-23(2)14-15-31(49)24(3)19-29(16-17-48)39(25(4)32(50)20-34(51)62-33)64-44-38(53)36(47(9)10)40(27(6)61-44)63-35-21-46(8,55)43(54)28(7)59-35. 5-1(3(7)8)2(6)4(9)10/h14-15,17-18,24-30,32-33,35-45,50,52-55H,13,16,19-22H2,1-12H3. 1-2,5-6H,(H,7,8)(H,9,10)/b15-14+,23-18+. /t24-,25+,26-,27-,28+,29+,30-,32-,33-,35+,36-,37-,38-,39-,40-,41-,42-,43+,44+,45-,46-. 1-,2-/m11/s1. InChI key: ICVKYYINQHWDLM-KBEWXLTPSA-N. Pictograms: GHS08. Signal Word: Danger. Hazard Statements: H317 - H334. Precautionary Statements: P261 - P272 - P280 - P284 - P302 + P352 - P304 + P340 + P312. Hazard Classifications: Resp. Sens. 1 - Skin Sens. 1. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Faceshields, Gloves.