TUG-1375 is an agonist of free fatty acid receptor 2 ( FFA2/GPR43 ), with a pK i of 6.69. TUG-1375 is inactive on FFA3, FFA4, PPARα , PPARγ , PPARδ , LXRα or LXRβIn VitroTUG-1375 exhibits pEC 50 of 7.11 in the cAMP FFA2 assay, also active on murine FFA2 orthologue (pEC 50 , 6.44 ± 0.13 in the cAMP assay). MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:pKi: 6.69 (FFA2).
Specifications and Purity: ≥99%
Molecular Formula: C22H19ClN2O4S
Molecular Weight: 442.9
PubChem CID: 138319694
Isomeric SMILES: CC1=C(C(=NO1)C)C2=CC=C(C=C2)C(=O)N3[C@@H](CS[C@@H]3C4=CC=CC=C4Cl)C(=O)O
- UPC:
- 41114621
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- T649206-50mg
- CAS:
- 2247372-59-2
- Product Size:
- 50mg
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