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trka (440-end), active, gst tagged human

TRKA (440-END) ACTIVE HUMAN GST TAGGED

Catalog No.
C005B-287576
Manufacturer No.
T4202-10UG
Manufacturer Name
Sigma-Aldrich
Quantity
1
Unit of Measure
EA

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Application TRKA (440-end), active, GST tagged human was used to study functional NGF signal transduction. Biochem/physiol Actions TRKA (440-end), active, GST tagged human is a 140 kD membrane-spanning protein tyrosine kinase that belongs to

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Application

TRKA (440-end), active, GST tagged human was used to study functional NGF signal transduction.

Biochem/physiol Actions

TRKA (440-end), active, GST tagged human is a 140 kD membrane-spanning protein tyrosine kinase that belongs to proto-oncogene family. TRKA facilitates the regulation of cell differentiation and survival via activating SHC1 and FRS2 which in turn activates a GRB2-Ras-MAPK cascade. It also plays a pivotal role in controlling NF-κ-B activation as well as transcription of genes involved in cell survival via PLCG1.

Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

Legal Information

PRECISIO is a registered trademark of Sigma-Aldrich Co. LLC

UPC:
41106103
Condition:
New
HazmatClass:
No
MPN:
T4202-10UG
CAS:
152787-58-1
Temperature Control Device:
Yes

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