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trioxsalen (c15-1698-373)

TRIOXSALEN (C005B-287245)

Catalog No.
C005B-287245
Manufacturer No.
T6137-1G
Manufacturer Name
Sigma-Aldrich
Quantity
1
Unit of Measure
GM

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Application Trioxsalen has been used for mutagenesis of N2 worms 4,5 . Trioxsalen has been used: to induce small deletion mutations in worms in combination with ultraviolet A (UVA) to induce interstrand crosslinks (ICLs) in DNA for the

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Application

Trioxsalen has been used for mutagenesis of N2 worms4,5.

Trioxsalen has been used:

  • to induce small deletion mutations in worms
  • in combination with ultraviolet A (UVA)
  • to induce interstrand crosslinks (ICLs) in DNA
  • for the preparation and photoactivation of trimethyl psoralen

Biochem/physiol Actions

Photochemical crosslinker of DNA that has been used as a probe for nucleic acid structure and function. Trioxsalen has also been used to crosslink DNA onto mica surfaces.

Trioxsalen (TRX) is a 4,5′,8-trimethylated psoralen analog, which belongs to the family of furocoumarins. It is mostly used to treat psoriasis.

Features and Benefits

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by Valeant. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Preparation Note

Trioxsalen is soluble in chloroform at 50 mg/ml and yields a clear, colorless to faint yellow solution.

UPC:
10161549
Condition:
New
HazmatClass:
Yes
MPN:
T6137-1G
CAS:
3902-71-4
Temperature Control Device:
Yes

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