General description
Tributylammonium pyrophosphate is a phosphorylating reagent used in the synthesis of modified dNTPs (deoxynucleoside triphosphates) which are important building blocks for the generation of DNA, RNA, functionalized nucleic acids.
Application
Reactant for:
- Enzymic synthesis of 3′-deoxy-apio-nucleic acid duplexes
- Synthesis of deoxynucleoside S-methylphosphonic acids
- Preparation of fluorescent non-nucleotide ATP analog N-methylanthraniloylamideethyl triphosphate
Tributylammonium pyrophosphate used as a phosphorylating reagent:
- In the synthesis of S′-deoxy-S′-methylphosphonic acid diphosphate along with 1, 1′-carbonyl diimidazole.
- In the synthesis of gram-scale level base-modified ribonucleoside-5′-O-triphosphates.
- In one-pot chemical synthesis of 2′-deoxynucleoside-5′-triphosphates with better protection.
- UPC:
- 12131600
- Condition:
- New
- HazmatClass:
- No
- MPN:
- P8533-1G
- CAS:
- 5975-18-8
akash.verma@cenmed.com
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