InformationTrametinib (GSK1120212, JTP-74057, Mekinist) DMSO solvate is a highly specific and potentMEK1/2inhibitor with IC50 of 0.92 nM/1.8 nM in cell-free assay. Trametinib activatesautophagyand inducesapoptosis.TargetsMEK1 (Cell-free assay); MEK2 (Cell-free assay) 0.92 nM; 1.8 nM.
Specifications and Purity: 10mM in DMSO
Molecular Formula: C28H29FIN5O5S
Molecular Weight: 693.53
PubChem CID: 50992434
Isomeric SMILES: CC1=C2C(=C(N(C1=O)C)NC3=C(C=C(C=C3)I)F)C(=O)N(C(=O)N2C4=CC=CC(=C4)NC(=O)C)C5CC5.CS(=O)C
- UPC:
- 51171610
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- T420824-1ml
- CAS:
- 1187431-43-1
- Product Size:
- 1ml
akash.verma@cenmed.com
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