Trabectedin is a tetrahydroisoquinoline alkaloid with potent antitumor activity. Trabectedin binds to the minor groove of DNA, blocks transcription of stress-induced proteins, induces DNA backbone cleavage and cancer cells apoptosis, and increases the generation of ROS in MCF-7 and MDA-MB-453 cells. Trabectedin has the potential for soft tissue sarcoma and ovarian cancer research.
Specifictaions: Moligand™, ≥98%
MDL Number: C39H43N3O11S
Molecular Formula: 761.84
PubChem CID: 108150
Isomeric SMILES: CC1=CC2=C([C@@H]3[C@@H]4[C@H]5C6=C(C(=C7C(=C6[C@@H](N4[C@H]([C@H](C2)N3C)O)COC(=O)[C@@]8(CS5)C9=CC(=C(C=C9CCN8)O)OC)OCO7)C)OC(=O)C)C(=C1OC)O
Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/T128049-SCI_033fb306fd03df748d1b3c2e1f780fee.pdf
- UPC:
- 42294514
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- T128049-10mg
- CAS:
- 114899-77-3
- Product Size:
- 10mg
- Health Hazards:
- Carcinogen,Toxic
- Hazard Statement Codes:
- H361
- Precautionary Statement Codes:
- P319
akash.verma@cenmed.com
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