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TORIN2 (C005B-312393)

Catalog No.
C005B-312393
Manufacturer No.
SML1224-25MG
Manufacturer Name
Sigma-Aldrich
Quantity
25
Unit of Measure
MG

Application Torin2 has been used: to examine its effect on LC3B-II levels in BORCS5- KO cells to determine its potent activity (IC 50  :less than 1 μ:M) against A2780-cis ovarian cancer cells in western blot analysis

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Application

Torin2 has been used:

  • to examine its effect on LC3B-II levels in BORCS5- KO cells
  • to determine its potent activity (IC50 less than 1 μM) against A2780-cis ovarian cancer cells
  • in western blot analysis

Biochem/physiol Actions

Torin2 is a highly potent and selective ATP-competitive mTOR inhibitor. Torin2 has an IC50 of 0.25 nM and 800-fold greater selectivity for mTOR than PI3K.

UPC:
12131602
Condition:
New
HazmatClass:
No
MPN:
SML1224-25MG
CAS:
1223001-51-1

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