TNG260 is a CoREST-selective deacetylase ( CoreDAC ) inhibitor. TNG260 inhibits HDAC1 with 10-fold selectivity over HDAC3 . TNG260 leads to HDAC1 inhibition, reverses anti-PD1 resistance driven by loss of STK11. TNG260 decreases intratumoral infiltration of neutrophils. TNG260 exhibits immune-mediated cell killingIC50& Target:HDAC1 HDAC3.
Molecular Formula: C20H18FN3O2S
Molecular Weight: 383.44
- UPC:
- 41116135
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- T650094-5mg
- CAS:
- 2935964-98-8
- Product Size:
- 5mg
akash.verma@cenmed.com
(732) 447-1115





