TMI-1 (C005B-432496)

Catalog No.: C005B-432496
Manufacturer No.: PZ0336-5MG
Manufacturer Name: Sigma-Aldrich
Quantity: 5
Unit of Measure: MG

Biochem/physiol Actions TMI-1 (WAY-171318) is potent inhibitor of disintegrin metalloenzyme 17 (ADAM17) also known as the tumor necrosis factor-α: (TNF-α:) converting enzyme (TACE), and matrix metalloprotease (MMP). TMI-1 potently

Enjoy exclusive benefits including discounted pricing on orders by contacting our Sales Executives to open an account. Contact Us

Description
Specifications

Biochem/physiol Actions

TMI-1 (WAY-171318) is potent inhibitor of disintegrin metalloenzyme 17 (ADAM17) also known as the tumor necrosis factor-α (TNF-α) converting enzyme (TACE), and matrix metalloprotease (MMP). TMI-1 potently inhibits LPS-induced TNF-α secretion in human primary monocytes, and human whole blood. TMI-1 selectively induces caspase-dependent apoptosis in triple negative (TN) and ERBB2-overexpressing breast tumor cell lines.

Other Notes

This compound was developed by Pfizer for Cytokines & Growth Factors research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.

Legal Information

Sold for research purposes under agreement from Pfizer Inc.

Pfizer is a registered trademark of Pfizer, Inc.

UPC:: 41105600
Condition:: New
HazmatClass:: No
MPN:: PZ0336-5MG
CAS:: 287403-39-8

Cenmed Satisfaction Guarantee

At Cenmed, your confidence and satisfaction are paramount. We guarantee the quality and reliability of our extensive range of clinical and laboratory supplies. If you're not completely satisfied with your purchase, we offer a straightforward return process and dedicated support to resolve your concerns promptly. Our commitment ensures that you can order with confidence, knowing that Cenmed is dedicated to superior service and customer satisfaction. Trust us to meet your needs with every order, backed by our promise of excellence. Learn more in Help & FAQs.

"Cenmed provides me access to the same products/services normally reserved for much larger labs than mine. I was presently surprised by their product offering."

LAB DIRECTOR

"We utilized Cenmed's capabilities for a variety of projects around the world. They are a valued partner and supplier."

PHARMACEUTICAL SUPPLY CHAIN LEADER

"The reps are very good at finding products for customers in this period of supply chain issues."

SCOTT BEHMAN

"Your customer service has been excellent and makes me excited about purchasing with Cenmed in the future!!"

PROCUREMENT + BILLING COORDINATOR AT PHARMA.

Akash Verma