Thiol-PEG4-Alcohol (C007B-232375)

Application：2-{2-[2-(2-Mercaptoethoxy)ethoxy]ethoxy}ethanol may be used in the synthesis of 2-(2-(2-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)thio)ethoxy)ethoxy)ethanol, an nitrobenzoxadiazole (NBD) analog of the anticancer agent 6-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)thio)hexan-1-ol (NBDHEX). This analog is a potent glutathione S-transferase (GST) and a potential therapeutic antimelanoma agent with enhanced water solubility and antitumor efficacy when compared to NBDHEX in a study. Oligo-ehtylene glycol of peptides and small molecules (PEGylation) PEG-disulfide formation ultra-thin protein-resistant monolayers Densely packed monolayer and a flexible-hydrophilic oligo ethylene glycol arm for avoiding non-specific adsorption.

Specifications and Purity: ≥97%

MDL Number: MFCD22574773

Molecular Formula: C8H18O4S

Molecular Weight: 210.29

PubChem CID: 10465720

Isomeric SMILES: C(COCCOCCOCCS)O

Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/M469947-SCI_5ba7d1074fbc7929742c0404e9ebe20c.pdf