Thiamet G is a potent and selective inhibitor of O-GlcNAcase (OGA), which acts to remove O-GlcNAc from modified proteins, with Ki of 20 nM for human OGA.Application:Thiamet G has been used as an O-GlcNAcase inhibitor:to treat human embryonic kidney 293 cells in order to study its effect on Wnt/beta-catenin signallingto treat lytically-replicating producerto incubate mice (C57BL/6) aortic segments to increase global O-GlcNAc levels.
Specifications and Purity: ≥99%
MDL Number: MFCD15144964
Molecular Formula: C9H16N2O4S
Molecular Weight: 248.3
PubChem CID: 135566354
Isomeric SMILES: CCN=C1N[C@@H]2[C@H]([C@@H]([C@H](O[C@@H]2S1)CO)O)O
Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/T129644-SCI_b5f43defc06da4472fe3c629fcf91ed6.pdf
- UPC:
- 12352113
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- T129644-5mg
- CAS:
- 1009816-48-1
- Product Size:
- 5mg
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