A potent and selective inhibitor of O-GlcNAcase (Ki = 21 nM); increases cellular O-GlcNAc-modified protein levels (EC50 = 30 nM) and blocks phosphorylation of tau protein both in cultured PC-12 cells and in rats (200 mg/kg/day); is orally bioavailable and effectively cross the blood brain barrier.
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- UPC:
- 51131507
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 13237-1
- CAS:
- 1009816-48-1
- Model Number:
- C832V83
- Temperature Control Device:
- Yes
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