Skip to main content
tffh 5 g

TFFH 5 G

Catalog No.
C005B-021101
Manufacturer No.
8510900005
Manufacturer Name
Novabiochem
Quantity
5
Unit of Measure
GR

Log in for pricing

TFFH is an in situ coupling reagents which smoothly converts protected amino acids to the corresponding acid fluoride in the presence of base [1] . Acid fluorides have proven are highly effective at coupling hindered amino acids such as

Enjoy exclusive benefits including discounted pricing on orders by contacting our Sales Executives to open an account. Contact Us

General description

TFFH is an in situ coupling reagents which smoothly converts protected amino acids to the corresponding acid fluoride in the presence of base [1]. Acid fluorides have proven are highly effective at coupling hindered amino acids such as α,α-disubstituted amino acids [2].

Associated Protocols and Technical Articles
Guide to Selection of Coupling Reagents

Literature references

[1] L. A. Carpino, et al. (1995) J. Am. Chem. Soc., 117, 5401.
[2] S. A. Triolo, et al. in ′Peptides 1996, Proc. of 24th European Peptide Symposium′, R. Ramage & R. Epton (Eds), Mayflower Scientific Ltd., Birmingham, 1998, pp. 839.

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Assay 1H-qNMR: ≥ 98.0 %
Ratio Cation/anion in 19F-NMR integration: lot specific result
1:5,7 to 1:6,3
Identity (IR): passes test

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Molecular Weight: 264.12. Empirical Formula: C5H12F7N2P. Quality Level: 200. product line: Novabiochem®. . form: solid. reaction suitability: reaction type: Coupling Reactions. manufacturer/tradename: Novabiochem®. . mp: 104-109 . °C. application(s): peptide synthesis. storage temp.: 2-8°C. InChI: 1S/C5H12FN2/c1-7(2)5(6)8(3)4/h1-4H3/q+1. InChI key: JILUGXGJYPRQPA-UHFFFAOYSA-N. Pictograms: GHS05,GHS07. Signal Word: Danger. Hazard Statements: H315 - H318 - H335. Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338. Hazard Classifications: Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3. Target Organs: Respiratory system. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.
UPC:
42202701
Condition:
New
HazmatClass:
No
MPN:
8510900005
CAS:
164298-23-1

Cenmed Satisfaction Guarantee
Cenmed Satisfaction Guarantee

At Cenmed, your confidence and satisfaction are paramount. We guarantee the quality and reliability of our extensive range of clinical and laboratory supplies. If you're not completely satisfied with your purchase, we offer a straightforward return process and dedicated support to resolve your concerns promptly. Our commitment ensures that you can order with confidence, knowing that Cenmed is dedicated to superior service and customer satisfaction. Trust us to meet your needs with every order, backed by our promise of excellence. Learn more in Help & FAQs.

Testimonial
"Cenmed provides me access to the same products/services normally reserved for much larger labs than mine. I was presently surprised by their product offering."

LAB DIRECTOR

Testimonial
"We utilized Cenmed's capabilities for a variety of projects around the world. They are a valued partner and supplier."

PHARMACEUTICAL SUPPLY CHAIN LEADER

Testimonial
"The reps are very good at finding products for customers in this period of supply chain issues."

SCOTT BEHMAN

Testimonial
"Your customer service has been excellent and makes me excited about purchasing with Cenmed in the future!!"

PROCUREMENT + BILLING COORDINATOR AT PHARMA.

Lab - Point of Care

Lab Equipment & Accessories

Chemicals, Stains and Reagents

Medical Equipment

!