TERT-BUTYLMAGNESIUM CHLORIDE 1.0M SOLUTION IN TETRAHYDROFURAN (C005B-056798)

General description

tert-Butylmagnesium chloride, an organomagnesium compound, is commonly known as Grignard reagent. It is a powerful carbon nucleophile mainly used for C-C bond formation.

Application

tert-Butylmagnesium chloride (1.0 M in THF) has been used in the preparation of tert-butylsulfinyl chloride.
It can be used in:

• Grignard metathesis reaction of 2,5-dibromo-3-hexylthiophene to form 2-bromo-5-magnesiobromo-3-hexylthiophene.
• A key step for the asymmetric synthesis of sulfinyl transfer agents using cinchona alkaloids quinine and quinidine as chiral auxiliaries.

Other Notes

Storage below 25°C may cause formation of crystalline magnesium salts. Moving container to a warm location and ocassional gentle swirling should redissolve the solid.

Molecular Weight: 116.87. Empirical Formula: C₄H₉ClMg. linearFormula: (CH₃)₃CMgCl. Quality Level: 200. reaction suitability: reaction type: Grignard Reaction. concentration: 1.0 . M in THF. density: 0.931 . g/mL . at 25 . °C. SMILES string: CC(C)(C)[Mg]Cl. InChI: 1S/C4H9.ClH.Mg/c1-4(2)3. . /h1-3H3. 1H. /q. . +1/p-1. InChI key: ZDRJSYVHDMFHSC-UHFFFAOYSA-M. Pictograms: GHS02,GHS05,GHS07,GHS08. Signal Word: Danger. Hazard Statements: H225 - H250 - H260 - H302 - H314 - H335 - H336 - H351. Precautionary Statements: P210 - P231 + P232 - P280 - P303 + P361 + P353 - P305 + P351 + P338 - P370 + P378. Hazard Classifications: Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Pyr. Liq. 1 - Skin Corr. 1B - Water-react 1. Supp Hazards: EUH019. Storage Class Code: 4.2 - Pyrophoric and self-heating hazardous materials. WGK: WGK 3. Flash Point(F): 1.4 °F - closed cup. Flash Point(C): -17 °C - closed cup. Personal Protective Equipment: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter.