akash.verma@cenmed.com
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Product Describtion:TCS 1102 is a potent, dual orexin receptor antagonist (Ki values are 0.2 and 3 nM for OX2 and OX1 receptors respectively). IC50 value: 0.2 nM (Ki, OX2 receptor); 3 nM (Ki, OX1 receptor) ；Target: OX2 and OX1 receptor TCS-1102 (10 and 20 mg/kg, i.p.) were found to decrease fear and anxiety in rats 14 days after exposure to footshock.Furthermore, TCS-1102 (10 mg/kg, i.p.) was found to have anxiolytic effects that were specific for HR when tested in the elevated T-maze.
Specifications and Purity: ≥98%(HPLC)
Molecular Formula: C₂₇H₂₆N₄O₂S
Molecular Weight: 470.59
PubChem CID: 11960895
Isomeric SMILES: CN1C2=CC=CC=C2N=C1SCC(=O)N3CCC[C@H]3C(=O)NC4=CC=CC=C4C5=CC=CC=C5
Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/T287352-SCI_d68daef1459fdf3926a8bc533a175e63.pdf
- UPC:
- 41103023
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- T287352-50mg
- CAS:
- 916141-36-1
- Product Size:
- 50mg
- Precautionary Statement Codes:
- P264
