TCO-PEG12-acid is a non-activated PEG derivative containing a TCO moiety and a terminal carboxylic acid. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. This reagent can react with tetrazine-containing compounds to form a stable covalent bond without the catalysis of Cu or elevated temperatures. The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is the fastest bioorthogonal reaction with exceptional selectivity. The hydrophilic PEG spacer increases solubility in aqueous media.
Specifications and Purity: ≥95%
- UPC:
- 12352319
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- T596738-100mg
- Product Size:
- 100mg
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