General description
An antioxidant flavonoid that scavenges superoxide (1.5 x 105 M-1 s-1) and suppresses the cytotoxicity of superoxide and hydrogen peroxide in Chinese hamster V79 cells.
An antioxidant flavonoid that suppresses the cytotoxicity of superoxide ions and hydrogen peroxide in Chinese hamster V79 cells.
Biochem/physiol Actions
Cell permeable: no
Flavonoid, antioxidant. Inhibits lipogenesis in cancer cells, most likely by targeting fatty acid synthase activity.
Primary Target
An antioxidant flavonoid that scavenges superoxide
Product does not compete with ATP.
Reversible: no
Packaging
Packaged under inert gas
Warning
Toxicity: Harmful (C)
Other Notes
Kostyuk, V.A., et al. 1998. Arch. Biochem. Biophys. 355, 43.
Bors, W., et al. 1995. Free Radic. Biol. Med. 19, 45.
Nakayama, T., et al. 1994. Cancer Res. 54, 1991s.
Nakayama, T., et al. 1993. Biochem. Pharmacol. 45, 265.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Molecular Weight: 304.25 (anhydrous basis). Empirical Formula: C15H12O7 · xH2O. Quality Level: 100. Assay: ≥. 95% (HPLC). form: solid. manufacturer/tradename: Calbiochem®. . storage condition: OK to freeze, protect from light. color: white to off-white. solubility: ethanol: 20 . mg/mL. shipped in: ambient. storage temp.: 2-8°C. SMILES string: O.O[C@@H]1[C@H](Oc2cc(O)cc(O)c2C1: O)c3ccc(O)c(O)c3. InChI: 1S/C15H12O7.H2O/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6. /h1-5,14-19,21H. 1H2/t14-,15+. /m0./s1. InChI key: DNQPGSVMBPSRIR-LDXVYITESA-N. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.- UPC:
- 51191518
- Condition:
- New
- HazmatClass:
- No
- MPN:
- 580553-25MG
- CAS:
- 24198-97-8
akash.verma@cenmed.com
(732) 447-1115





