TAS-119 is a potent Aurora A inhibitor with an IC50 of 1.0 nM. TAS-119 shows high selectivity for Aurora A over other protein kinases, including Aurora B (IC50 of 95 nM). TAS-119 has potent antitumor activites.
Specifictaions: Moligand™, ≥98%
MDL Number: C23H22Cl2FN5O3
Molecular Formula: 506.36
PubChem CID: 71696703
Isomeric SMILES: CC1=CC(=NN1)NC2=C(C=CC(=N2)CC3(CCN(CC3)C(=O)C4=C(C(=CC=C4)Cl)Cl)C(=O)O)F
- UPC:
- 41112802
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- V614743-10mg
- CAS:
- 1453099-83-6
- Product Size:
- 10mg
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