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tapi-2 acetate salt

TAPI-2 ACETATE SALT

Catalog No.
C005B-313399
Manufacturer No.
SML0420-1MG
Manufacturer Name
Sigma-Aldrich
Quantity
1
Unit of Measure
MG

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Application TAPI-2 acetate salt has been used to inhibit protease activity in HepG2 cells. Biochem/physiol Actions TAPI-2 is a potent inhibitor matrix metalloproteinases and TACE (TNF-α: convertase/ADAM17/α:-secretase).

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Application

TAPI-2 acetate salt has been used to inhibit protease activity in HepG2 cells.

Biochem/physiol Actions

TAPI-2 is a potent inhibitor matrix metalloproteinases and TACE (TNF-α convertase/ADAM17/α-secretase). It blocks the shedding of several cell surface proteins such as β-amyloid precursor protein, inhibits TNF-α release as well as a diverse variety of membrane-anchored cytokines, cell adhesion molecules, receptors, ligands. TAPI-2 is considered a fairly broad metalloproteinase inhibitor, but it much more selective for TACE than GM6001.

Features and Benefits

This compound is featured on the Cytokine Receptors (Tumor Necrosis Receptor Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

UPC:
51191804
Condition:
New
HazmatClass:
No
MPN:
SML0420-1MG
CAS:
689284-12-6
Temperature Control Device:
Yes

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