TAPI-0

Catalog No.: C005B-312301
Manufacturer No.: SML1292-1MG
Manufacturer Name: Sigma-Aldrich
Quantity: 1
Unit of Measure: MG

Biochem/physiol Actions TAPI-0 inhibit peptide deformylase (PDF) activity and retard the growth Chlamydia trachomatis , which is an obligate intracellular bacterium responsible for a number of human diseases. TAPI-0 is a metalloproteinase

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Description
Specifications

Biochem/physiol Actions

TAPI-0 inhibit peptide deformylase (PDF) activity and retard the growth Chlamydia trachomatis, which is an obligate intracellular bacterium responsible for a number of human diseases.

TAPI-0 is a metalloproteinase inhibitor with selectivity for TACE (TNF-α converting enzyme/ADAM17; IC₅₀ = 100 nM). TAPI-0 also inhibits of collagenase and gelatinase. Although not specific for TACE, TAPI-0 is extensively used to block TACE-mediated TNF-α shedding.

UPC:: 10161817
Condition:: New
HazmatClass:: Yes
MPN:: SML1292-1MG
CAS:: 163958-73-4
Temperature Control Device:: Yes

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