TAMOXIFEN

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Protein kinase C inhibitor. Induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response modifiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells.

Molecular Weight: 371.51. Empirical Formula: C₂₆H₂₉NO. linearFormula: C₆H₅C(C₂H₅): C(C₆H₅)C₆H₄OCH₂CH₂N(CH₃)₂. grade: analytical standard. Quality Level: 100. Assay: ≥. 98.0% (HPLC). shelf life: limited shelf life, expiry date on the label. technique(s): HPLC: suitable, gas chromatography (GC): suitable. impurities: ≤. 0.5% water. mp: 97-98 . °C (lit.). application(s): forensics and toxicology
pharmaceutical (small molecule). format: neat. storage temp.: 2-8°C. SMILES string: CC\C(c1ccccc1): C(/c2ccccc2)c3ccc(OCCN(C)C)cc3. InChI: 1S/C26H29NO/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)28-20-19-27(2)3/h5-18H,4,19-20H2,1-3H3/b26-25-. InChI key: NKANXQFJJICGDU-QPLCGJKRSA-N. Gene Information: human ... ESR1(2099). Pictograms: GHS08,GHS09. Signal Word: Danger. Hazard Statements: H350 - H360 - H410. Precautionary Statements: P201 - P273 - P308 + P313. Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A - Repr. 1B. Storage Class Code: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.