Biochem/physiol Actions TAK-901 is a potent and tight-binding Aurora B kinase inhibitor. TAK-901 targets multiple kinases in vitro , but appears to mainly target Aurora B in cells and in vivo .
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TAK-901 is a potent and tight-binding Aurora B kinase inhibitor. TAK-901 targets multiple kinases in vitro, but appears to mainly target Aurora B in cells and in vivo. TAK-901 suppresses cellular histone H3 phosphorylation and induced polyploidy.
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