SW157765 (C007B-418272)

Catalog No.: C007B-418272
Manufacturer No.: S648694-100mg
Manufacturer Name: Aladdin Scientific
Quantity: 1
Unit of Measure: EA

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Description
Specifications

SW157765 is a selective non-canonical glucose transporter GLUT8 (SLC2A8) inhibitor. KRAS/KEAP1 double mutant NSCLC cells are selectively sensitive to the SW157765, due to the convergent consequences of dual KRAS and NRF2 modulation of metabolic and xenobiotic gene regulatory programs.In VitroSW157765-sensitive NSCLC cell lines are also selectively sensitive to glucose deprivation and to GLUT8 depletion. SW157765 selectively inhibits fluorescent 2-deoxyglucose (2DG) uptake in SW157765-sensitive cells in a dose-dependent manner. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:Solid.

Specifications and Purity: ≥98%

Molecular Formula: C19H13N3O3

Molecular Weight: 331.32

PubChem CID: 782267

Isomeric SMILES: C1=COC(=C1)/C=C/C(=O)NC2=CC3=C(C=C2)OC(=N3)C4=CC=NC=C4

UPC:: 41103301
Condition:: New
HazmatClass:: No
WeightUOM:: LB
MPN:: S648694-100mg
CAS:: 332063-87-3
Product Size:: 100mg

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