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SW-044248 (C007B-273233)

Catalog No.
C007B-273233
Manufacturer No.
S424481-1ml
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA

InformationSW-044248 is a non-canonicalTop1inhibitor with a pattern of selective toxicity for NSCLC cells.TargetsTopo1In vitroSW044248 is selectively toxic for some NSCLC cell lines. SW044248 rapidly inhibits transcription, translation and DNA

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InformationSW-044248 is a non-canonicalTop1inhibitor with a pattern of selective toxicity for NSCLC cells.TargetsTopo1In vitroSW044248 is selectively toxic for some NSCLC cell lines. SW044248 rapidly inhibits transcription, translation and DNA synthesis in sensitive cells but not insensitive cells. The acute transcriptional response to SW044248 correlates with the response to agents that cause DNA damage.Cell Research(from reference)Cell lines:NSCLC cell lines Incubation Time:96 h.

Specifications and Purity: 10mM in DMSO

Molecular Formula: C22H23N5O2S

Molecular Weight: 421.52

PubChem CID: 3152990

Isomeric SMILES: CCC(C(=O)NC1=CC=CC=C1OC)SC2=NC3=C(C4=CC=CC=C4N3CC)N=N2

UPC:
41116301
Condition:
New
HazmatClass:
No
WeightUOM:
LB
MPN:
S424481-1ml
CAS:
522650-83-5
Product Size:
1ml

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