Sulprostone is a metabolism resistant synthetic analog of PGE2. It is a selective agonist for EP3 receptors with a Ki value of 0.35 nM at the human recombinant EP3-III receptor and an IC50 of 0.01 µM for the inhibition of PGE2 binding. Sulprostone is a potent stimulator of uterine smooth muscle contractions with high abortifacient activity.
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- UPC:
- 51172004
- HazmatClass:
- Yes
- WeightUOM:
- LB
- MPN:
- 14765-5
- CAS:
- 60325-46-4
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