General description
Streptokinase is an extracellular enzyme, a single-chain polypeptide produced by several strains of β-hemolytic Streptococci. It is composed of multiple structural domains like α-, β-, and γ-domains that are involved in various functions.
Application
Streptokinase C from Streptococcus sp. has been used to quantitate the survival of Staphylococcus aureus in whole human blood.
Biochem/physiol Actions
Streptokinase shows fibrinolytic activity by triggering the circulatory plasminogen either via a fibrin-dependent or fibrin-independent mechanism. Streptokinase has been studied majorly in terms of its therapeutic efficacy and treating myocardial infarction to dissolve clots.
Unit Definition
One unit will liquify a standard clot of fibrinogen, plasminogen, and thrombin at pH 7.5 at 37 °C in 10 min.
Physical form
Lyophilized powder containing approx. 50% bovine serum albumin (total protein by biuret) with sodium glutamate.
- UPC:
- 51201639
- Condition:
- New
- HazmatClass:
- No
- MPN:
- S0577-10KU
- Temperature Control Device:
- Yes
akash.verma@cenmed.com
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