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STREPTOKINASE C FROM STREPTOCOCCUS EQUISIMILIS RECOMBINANT EXPRESSED IN E. COLI (C005B-377819)

Catalog No.
C005B-377819
Manufacturer No.
S0577-10KU
Manufacturer Name
Sigma-Aldrich
Quantity
10000
Unit of Measure
UN

General description Streptokinase is an extracellular enzyme, a single-chain polypeptide produced by several strains of β:-hemolytic Streptococci . It is composed of multiple structural domains like α:-, β:-, and γ:-domains that

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General description

Streptokinase is an extracellular enzyme, a single-chain polypeptide produced by several strains of β-hemolytic Streptococci. It is composed of multiple structural domains like α-, β-, and γ-domains that are involved in various functions.

Application

Streptokinase C from Streptococcus sp. has been used to quantitate the survival of Staphylococcus aureus in whole human blood.

Biochem/physiol Actions

Streptokinase shows fibrinolytic activity by triggering the circulatory plasminogen either via a fibrin-dependent or fibrin-independent mechanism. Streptokinase has been studied majorly in terms of its therapeutic efficacy and treating myocardial infarction to dissolve clots.

Unit Definition

One unit will liquify a standard clot of fibrinogen, plasminogen, and thrombin at pH 7.5 at 37 °C in 10 min.

Physical form

Lyophilized powder containing approx. 50% bovine serum albumin (total protein by biuret) with sodium glutamate.

UPC:
51201639
Condition:
New
HazmatClass:
No
MPN:
S0577-10KU
Temperature Control Device:
Yes

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