Stafib-2 is a potent and selctive inhibitor of the transcription factor STAT5b , with an IC 50 of 82 nM and 1.7 μM for STAT5b and STAT5a , respectively. Stafib-2 exhibits poor cell permeabilityIn VitroStafib-2 has an extremely high affinity for STAT5b (K i =8.8 nM). Stafib-2 (3-10 μM; 4-48 h) does not show significant activity in K562 and MDA-MB-231 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:IC50: 82 nM (STAT5b).
Specifications and Purity: ≥98%
Molecular Formula: C28H26N2O12P2
Molecular Weight: 644.46
PubChem CID: 129896883
Isomeric SMILES: C1=CC=C(C=C1)OC2=CC=C(C=C2)NC(=O)C3=CC=C(C=C3)OCC(=O)NCC4=CC(=C(C=C4)OP(=O)(O)O)OP(=O)(O)O
- UPC:
- 10161550
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- S648231-25mg
- CAS:
- 2097938-74-2
- Product Size:
- 25mg
akash.verma@cenmed.com
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