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ss-208 (c09-1169-727)

SS-208 (C007B-417898)

Catalog No.
C007B-417898
Manufacturer No.
S647126-1mg
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA

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SS-208 is a selective HDAC6 inhibitor, with an IC 50 of 12 nM. SS-208 possesses anti-tumor activity in melanomaIn VivoSS-208 (25 mg/kg, ip) significantly reduces the tumor growth in melanoma murine model . MCE has not independently confirmed the

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SS-208 is a selective HDAC6 inhibitor, with an IC 50 of 12 nM. SS-208 possesses anti-tumor activity in melanomaIn VivoSS-208 (25 mg/kg, ip) significantly reduces the tumor growth in melanoma murine model . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: C57BL/6 mice injected immunogenic murine SM1 melanoma cells subcutaneously . Dosage: 25 mg/kg. Administration: IP on day 4, 7, 12, 15 and 18. Result: Significantly reduced the tumor growth.Form:SolidIC50& Target:HDAC6 12 nM (IC 50 ) HDAC8 1.23 μM (IC 50 ) HDAC1 1.39 μM (IC 50 ) HDAC11 5.12 μM (IC 50 ) HDAC5 6.91 μM (IC 50 ) HDAC7 8.34 μM (IC 50 ).

Specifications and Purity: ≥98%

Molecular Formula: C13H11Cl2N3O4

Molecular Weight: 344.15

PubChem CID: 135348858

Isomeric SMILES: C1=CC(=C(C=C1C(=O)NCCC2=CC(=NO2)C(=O)NO)Cl)Cl

UPC:
42202202
Condition:
New
HazmatClass:
No
WeightUOM:
LB
MPN:
S647126-1mg
CAS:
2245942-72-5
Product Size:
1mg

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