Src Inhibitor 3 is a potent, orally active c-terminal Src kinase (CSK) with IC 50 values below 3 nM and 4 nM in CSK HTRF and Caliper assay, respectively. Src Inhibitor 3 shows the ability to increase T cell proliferation induced by T cell receptor signalingIn VivoSrc Inhibitor 3 reduces inhibitory LCK phosphorylation in vivo upon oral dosing and shows the ability to enhance T cell activation in response to antigen stimulation . MCE has not independently confirmed the accuracy of these methods. They are for reference only.IC50& Target:IC50: <3 nM (c-terminal Src kinase in CSK HTRF assay), 4 nM (c-terminal Src kinase in Caliper assay).
Specifications and Purity: 10mM in DMSO
Molecular Formula: C34H32ClFN8O4
Molecular Weight: 671.12
- UPC:
- 51131615
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- S655271-1ml
- CAS:
- 2380027-49-4
- Product Size:
- 1ml
akash.verma@cenmed.com
(732) 447-1115





