SPOP-IN-6b dihydrochloride is a potent speckle-type POZ protein (SPOP) inhibitor with an IC 50 of 3.58 μM.Appearance:SolidIn Vitro:SPOP-IN-6b dihydrochloride shows IC 50 s of 2-10.2 μM for A498, Caki-2, Ketr-3, 769-P, 0S-RC-2, and 786-0 cells. SPOP-IN-6b (0.1-3.0 μM; 10 hours) dihydrochloride can suppress SPOP activity, and then increase suppression cancer substrate protein PTENIn Vivo:SPOP-IN-6b (40-80mg/kg; intraperitoneal injection; daily; for 25 days; nude mice) dihydrochloride can slow down the growth of tumour by suppressing SPOP. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Biological Activity:SPOP-IN-6b dihydrochloride is a potent speckle-type POZ protein (SPOP) inhibitor with an IC 50 of 3.58 μM.
Specifications and Purity: ≥99%
Molecular Formula: C28H34Cl2N6O3
Molecular Weight: 573.51
- UPC:
- 12141901
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- S658950-25mg
- Product Size:
- 25mg
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