SPHOS PD G3 97% (C005B-018224)

General description

SPhos Pd G3 is a third-generation (G3) Buchwald precatalyst that can be used in cross-coupling reactions for the formation of C-C, C-N, C-O, C-F, C-CF₃, and C-S bonds. It is air-, moisture-, and thermally stable and is highly soluble in a wide range of common organic solvents. Some of its unique features include lower catalyst loadings, shorter reaction time, efficient formation of the active catalytic species, and accurate control of ligand: palladium ratio.

Application

Pd catalyst for cross-coupling

SPhos Pd G3 can be used as a precatalyst in the Suzuki–Miyaura catalyst–transfer polymerization (SCTP) reaction of a wide spectrum of monomers, including electron-rich to electron-deficient (hetero)arenes. It is also used as a catalyst in the formation of a Csp³â€“Csp² bond between sterically hindered boronic hemiester and quinone diazide, which is the key intermediate step in the enantioselective synthesis of azamerone.

Molecular Weight: 780.26. Empirical Formula: C₃₉H₄₈NO₅PPdS. Quality Level: 100. Assay: 97%. form: solid. feature: generation 3. reaction suitability: core: palladium, reaction type: Buchwald-Hartwig Cross Coupling Reaction, reaction type: Heck Reaction, reaction type: Hiyama Coupling, reaction type: Negishi Coupling, reaction type: Sonogashira Coupling, reaction type: Stille Coupling, reaction type: Suzuki-Miyaura Coupling, reagent type: catalyst
reaction type: Cross Couplings. mp: 197-214 . °C. functional group: phosphine. storage temp.: 2-8°C. SMILES string: CS(: O)(: O)O[Pd]c1ccccc1-c2ccccc2N.COc3cccc(OC)c3-c4ccccc4P(C5CCCCC5)C6CCCCC6. InChI: 1S/C26H35O2P.C12H10N.CH4O3S.Pd/c1-27-23-17-11-18-24(28-2)26(23)22-16-9-10-19-25(22)29(20-12-5-3-6-13-20)21-14-7-4-8-15-21. 13-12-9-5-4-8-11(12)10-6-2-1-3-7-10. 1-5(2,3)4. /h9-11,16-21H,3-8,12-15H2,1-2H3. 1-6,8-9H,13H2. 1H3,(H,2,3,4). /q. . . +1/p-1. InChI key: SCWODMZBSVVMRH-UHFFFAOYSA-M. Pictograms: GHS07. Signal Word: Warning. Hazard Statements: H315 - H319 - H335. Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338. Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3. Target Organs: Respiratory system. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.