SPERMINE >= 99.0% (GC) (C005B-058562)

Application

Spermine, a polycationic biogenic polyamine derived from spermidine, may be used in a wide variety of biological applications as a supplement or regulatory agent.Used as co-matrix with DHB for MALDI-MS of sialylated glycans in negative ion mode.

Biochem/physiol Actions

Mixed NMDA glutamate receptor agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).

Molecular Weight: 202.34. Empirical Formula: C₁₀H₂₆N₄. linearFormula: NH₂(CH₂)₃NH(CH₂)₄NH(CH₂)₃NH₂. biological source: microbial, synthetic. Quality Level: 200. Assay: ≥. 99.0% (GC). form: crystalline (chunks). impurities: ≤. 0.5% spermidine. bp: 150 . °C/5 . mmHg (lit.). mp: 28-30 (lit.). solubility: water: 0.05 . g/mL, clear, colorless. anion traces: carbonate (CO₃^2-): ≤. 5000 . mg/kg. storage temp.: 2-8°C. SMILES string: [H]N(CCCN)CCCCN([H])CCCN. InChI: 1S/C10H26N4/c11-5-3-9-13-7-1-2-8-14-10-4-6-12/h13-14H,1-12H2. InChI key: PFNFFQXMRSDOHW-UHFFFAOYSA-N. Pictograms: GHS05. Signal Word: Danger. Hazard Statements: H314. Precautionary Statements: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363. Hazard Classifications: Eye Dam. 1 - Skin Corr. 1B. Storage Class Code: 8A - Combustible, corrosive hazardous materials. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges.