SODIUM CYANOBOROHYDRIDE 1.0M SOLUTION IN TETRAHYDROFURAN (C005B-028190)

General description

Sodium cyanoborohydride is a versatile reducing agent stable in aqueous solution at pH 7.2. It is a weaker reducing agent as compared to NaBH₄. It effectively reduces Schiff bases. NaCNBH₄ participates in the reductive methylation for the efficient and selective conversion of the e-amino groups of lysyl residues in proteins to the mono- and dimethyl derivatives.

Application

Reactant for:

• Direct conversion of heterocyclic aldehydes to esters (oxidizing behavior)
• Reductive amination reactions
• Intramolecular reductive cyclization reactions
• Reductions reactions
• Preparation of dicyanoborate-based ionic liquids as hypergolic fluids for bipropellants

Sodium cyanoborohydride may be used in the following studies:

• As reducing agent for the in vitro radiolabeling of proteins by reductive alkylation.
• Reduction of aldehydes and ketones.
• Selective deoxygenation of aldehydes and ketones.
• Preparation of colloidal gold particles of varying sizes.

Molecular Weight: 62.84. Empirical Formula: CH₃BNNa. linearFormula: NaBH₃CN. Quality Level: 200. reaction suitability: reagent type: reductant. concentration: 1.0 . M in THF. solubility: THF: soluble(lit.), alcohol: soluble(lit.), hydrocarbons: insoluble(lit.), water: soluble(lit.). density: 0.915 . g/mL . at 25 . °C. SMILES string: [Na+].[H][B-]([H])([H])C#N. InChI: 1S/CH3BN.Na/c2-1-3. /h2H3. /q-1. +1. InChI key: CVDUGUOQTVTBJH-UHFFFAOYSA-N. Pictograms: GHS02,GHS05,GHS06,GHS08,GHS09. Signal Word: Danger. Hazard Statements: H225 - H260 - H301 + H311 + H331 - H314 - H335 - H336 - H351 - H410. Precautionary Statements: P210 - P231 + P232 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338. Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - Water-react 1. Supp Hazards: EUH019. Storage Class Code: 4.3 - Hazardous materials, which set free flammable gases upon contact with water. WGK: WGK 3. Flash Point(F): -4.0 °F. Flash Point(C): -20 °C.